Historical Southern Families is a twenty-three-volume series of authoritative genealogies covering a broad spectrum of Southern families. The series was compiled by the late distinguished genealogist John Bennett Boddie and completed by his wife. Each volume contains a number of genealogies running from a few pages to as many as several dozen or more. Following are the main families found in this volume and the geographical locations associated with each of them.

Bruner and Miller of KY; Clements of NC; Eggleston of VA; Etheredge and Wright of AL and other Southern States; Ford, Mallory, and Milstead of VA and KY; Grubb of PA and DE; Miller of SC; Overton of GA; Thomas Rose of Surry; and Ruffin of VA, NC, TN, and MO.